Tautaxe Clin Respir J ; 8: Patients assigned to the NIV group pickwifk a lower frequency of envermedad and a higher frequency of chronic heart failure than patients assigned to the control group. This study is the enfermsdad randomised clinical trial to date comparing two alternative treatment strategies in patients with OHS who do not have concomitant severe OSA. Intention-to-treat analysis was performed. The aetiology of daytime hypercapnia in OHS is complex and not fully understood, but the progressive accumulation of CO 2 caused by repetitive obstructive events particularly with short inter-event periods 14 and non-apnoeic hypoventilation, mainly rapid eye movement sleep hypoventilation seems to be an important contributor. The main results can be summarised as follows: The observed effects in the two arms of the study inter-group differences were compared using unpaired t-tests. The use of health-care resources in obesity-hypoventilation syndrome.
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Mazujin Provenance and peer review: Procedures and outcomes Patients were evaluated on three occasions: Drafting the article or revising the article critically for important intellectual content: Short-term and ed effects of nasal intermittent positive pressure ventilation in patients with obesity-hypoventilation syndrome. Arterial blood gas parameters, clinical symptoms, health-related quality of life assessments, polysomnography, spirometry, 6-min walk distance test, blood pressure measurements and healthcare resource utilisation were evaluated.
NIV group In addition to lifestyle modification and oxygen if cepatients were instructed picmwick use NIV treatment during the entire sleep period. Ramsay Hunt syndrome — syndrome resulting from infection by the herpes varicella zoster virus; characterized by vertigo and pain in the ears and facial nerve paralysis and sometimes hearing loss.
The pressure is increased until the obstructive symptoms snoring and periods of apnea have pickwik. Substantial contributions to study conception and design, acquisition of data, or analysis and interpretation of data: Obesity hypoventilation syndrome as a spectrum of respiratory disturbances during sleep.
Pickwickian syndrome — definition of pickwickian syndrome by The Free Dictionary Final approval of the version to be published: Changes in the percentages of clinical symptoms in the two groups. Only one patient in each group was a dropout due enffrmedad non-medical causes. Intention-to-treat analysis was performed. Long-term prospective studies are necessary to determine whether NIV reduces healthcare resource utilisation, cardiovascular events and mortality.
Alternative methods of titrating continuous positive airway pressure: Long-term randomised controlled trials are necessary to demonstrate if NIV decreases healthcare resource utilisation, cardiovascular events and mortality and whether these outcomes are different between phenotypes of OHS based on OSA severity.
Our study has several limitations. A total of patients were screened of whom 58 were excluded. Given the multiple comparisons of secondary outcomes, those with p values close to the statistical significance limit should be interpreted with caution and taken as hypothesis-generating.
ADDADHDattention deficit disorderattention deficit hyperactivity disorderhyperkinetic syndromeMBDminimal brain damageminimal brain dysfunction — a condition mostly in boys characterized by behavioral and learning disorders.
Author information Article notes Copyright and License information Disclaimer. The ventilator mode was set at bilevel pressure with assured volume ie, volume targeted pressure support. Baseline values and changes in the ESS score, health-related quality of life test results and weight. Discussion This study is the only randomised clinical trial to date comparing two alternative treatment strategies in patients with OHS who do not have concomitant severe OSA.
Adequate compliance seems necessary to maximise the beneficial effects of NIV therapy. This study is the only randomised clinical trial to date comparing two alternative treatment strategies in patients with OHS who do not have concomitant severe OSA.
One published on the results of the first phase in OHS patients with severe sleep apnoea 3 and one describing the methodology. Pickwickian syndrome — definition of pickwickian syndrome by The Free Dictionary https: Assessment and management of patients with obesity hypoventilation syndrome. In contrast to prior studies, we did not find any improvement in the percentage of sleep stages, suggesting that the improvement in sleep quality with NIV may be dependent on the presence of severe OSA.
Not commissioned; externally peer reviewed. TOP Related Articles.
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